GSK signs agreement to support pandemic preparedness in Europe

For media and investors only

- GSK will supply Adjupanrix to 12 participating European countries

- The agreement is for the reservation of future production and supply of Adjupanrix in the event of an influenza pandemic

- This latest agreement further strengthens GSK’s leadership in influenza pandemic preparedness following contracts with the US, WHO, and Canada

GSK plc (LSE/NYSE: GSK) today announced it had signed a framework contract with the European Commission’s (EC) Health Emergency Preparedness and Response Authority (HERA) for the reservation of future production and supply of 85 million doses of its pandemic influenza vaccine Adjupanrix [pandemic influenza vaccine (split virion, inactivated, adjuvanted)].

This is one of the first contracts signed by HERA since it was established in September 2021. Its core mission is to prevent, detect, and rapidly respond to health emergencies through working closely with other EC and national health agencies, industry and international partners to improve Europe’s readiness for health emergencies.

An influenza pandemic is a global epidemic caused by a new influenza strain to which there is little or no pre-existing immunity in the human population. Influenza pandemics are impossible to predict, and they may be mild or cause severe disease or death 1.

Welcoming this contract, Roger Connor, President Vaccines and Global Health, GSK, said:

I’m delighted that HERA has chosen GSK as a key partner in pandemic flu preparedness. This contract follows three other agreements GSK has made, in the US, Canada and with the WHO. These agreements leverage GSK’s world class global vaccine manufacturing network to continue our long-standing partnerships on pandemic preparedness and response. We have all seen the devastating human, economic and social consequences of a pandemic and the important part that vaccines are playing in helping us return to normal life. Through this agreement for 85m doses, we can help the EU and European countries, as well as other countries and regions, be better prepared for future pandemics.

This agreement with HERA concludes a series of contracts secured by GSK this year, under which it could provide at least 200 million doses of pandemic influenza vaccine to governments around the world. In February 2022 GSK extended its pandemic influenza vaccine stockpile contract with the United States Government 2. This was followed by a renewed agreement, in June, for supply of pandemic influenza vaccines to the World Health Organization (WHO), and in July a contract with the Government of Canada for both seasonal and pandemic influenza vaccines.

GSK is a global biopharma company with a purpose to unite science, technology, and talent to get ahead of disease together. Find out more at gsk.com/company

1 http://www.euro.who.int/en/health-topics/communicable-diseases... accessed Sept 25 2019

2 Contract awarded to GSK by the Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority; Contract number 75A50122D00002.

Cautionary statement regarding forward-looking statements

GSK cautions investors that any forward-looking statements or projections made by GSK, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Such factors include, but are not limited to, those described in the Company's Annual Report on Form 20-F for 2021, GSK’s Q2 Results for 2022 and any impacts of the COVID-19 pandemic.